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At 14 years of age, Hopkins fell into the acting business when his mother brought him to a cattle-call audition in New York for the Warner Bros. featureLean on Me, a starring role as Thomas Samms, a misguided drug-abusing high school student. His next project Juice, directed by Ernest R. Dickerson, had him starring as Steel alongside Khalil Kain, Omar Epps and Tupac Shakur. Hopkins subsequently starred in the HBO worldwide release "Strapped", that would be Forest Whitaker's directorial debut. Over the next two years, Hopkins appeared in episodes of "Murder One" and "Moesha", and six episodes as Dupree on "The Wayans Brothers" series, before finishing production on his next film "How to Be a Player", starring opposite Bill Bellamy and comedian Pierre Edwards.